Tepadina (Thiotepa)is an alkylating agent used with other medicines in the conditioning regimen before hematopoietic stem cell transplantation (HSCT).
Indication and Usage:
To reduce the risk of graft rejection when used in conjunction with high-dose busulfan and cyclophosphamide as a preparative regimen for allogeneic hematopoietic progenitor (stem) cell transplantation (HSCT) for pediatric patients with class 3 beta-thalassemia.
For treatment of adenocarcinoma of the breast or ovary.
For controlling intracavitary effusions secondary to diffuse or localized neoplastic diseases of various serosal cavities.
For treatment of superficial papillary carcinoma of the urinary bladder. (Information are based on FDA)
Side Effects:
Common side effects of Tepadina includes:
Increased risk of getting an infection.
Breathlessness and looking pale.
Bruising, bleeding gums or nosebleeds.
Tiredness and weakness (fatigue) during and after treatment.