Kineret (anakinra) is a recombinant, nonglycosylated form of the human interleukin-1 receptor antagonist (IL-1Ra). Kineret differs from native human IL-1Ra in that it has the addition of a single methionine residue at its amino terminus. Kineret consists of 153 amino acids and has a molecular weight of 17.3 kilodaltons. It is produced by recombinant DNA technology using an E coli bacterial expression system.
Kineret (anakinra) reduces the actions of chemicals in the body that are involved in inflammatory and immune responses.
Kineret is used to treat the symptoms of moderate to severe rheumatoid arthritis in adults. It may also help slow the progress of the disease. Kineret is usually given after other arthritis medications have been tried without successful treatment of symptoms.
